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KMID : 1137820100310050412
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의공학회지
2010 Volume.31 No. 5 p.412 ~ p.416
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Preliminary Study on Magnetic Resonance Temperature Measurement using Brain-Metabolite Phantom
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Han Yong-Hee
Jang Moo-Young
Mun Chi-Woong
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Abstract
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In this study, we measured the chemical shift change of metabolite peaks in the brain-metabolite phantom according to the temperature variation using nuclear magnetic resonance(NMR). The temperature range in NMR system was controled from 25 to 80 (5 step) by internal temperature controller. Temperature coefficients of each metabolite peaks were also calculated from the measured chemical shift depending on the temperature. The chemical shift changes depending on temperature were validated by linear regression method for each metabolite peaks. The temperature coefficients of , Cho, Cr, NAA, and Lac were 0.0086, 0.0088, 0.0091, 0.0089, and 0.0088ppm/, respectively. This study shows that chemical shift change of brain metabolite and temperature variation have linear relationship each other. This also makes authors believe that brain temperature measurement is possible using MR spectroscopic imaging technique.
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KEYWORD
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brain-metabolite, temperature coefficient, nuclear magnetic resonance, chemical shift
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